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The Master Schedule for Every Preclinical Study

Zentixs Previa brings study design, dosing schedules, animal grouping, and regulatory compliance into one master schedule, always audit-ready from protocol to report.

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Built for the Rigor of Preclinical Science

Zentixs Previa is purpose-built for animal-based preclinical research. Whether you are running a 7-day dose range finder or a 26-week chronic toxicity study, Previa handles every study type — single dose, repeat dose, genotoxicity, safety pharmacology, and carcinogenicity — with precision and compliance at every step.

From IACUC submission to final study report, every action is timestamped, attributed, and audit-ready. Eliminate paper-based chaos and replace it with structured, traceable electronic workflows.

Protocol-Driven

Build study protocols aligned with GLP, OECD, and ICH guidelines from day one

Team Collaboration

Role-based access for study directors, PIs, technicians, and QA auditors

Centralized Data

All raw data, deviations, and observations in a single validated repository

Smart Analytics

Automated summaries, trend reports, and TK calculations reduce manual effort.

Every Step. Fully Controlled.

From first protocol draft to final signed report — Previa owns every step of your preclinical study lifecycle.

01

Study Creation

Initiate studies with structured protocol templates. Define study type (acute, sub-acute, chronic), species, strain, test article details, and regulatory basis — GLP, non-GLP, or exploratory. Auto-generate unique study identifiers with full version control.

Protocol DesignStudy NumberTest ArticleRegulatory Framework
02

Review & Approval

Route protocols through configurable review chains — study director, QA, sponsor, and management. Capture 21 CFR Part 11 compliant e-signatures at every stage. Automated reminders prevent bottlenecks.

Multi-level ReviewE-SignaturesQA OversightSponsor Approval
03

Study Director Appointment

Appoint a GLP-qualified Study Director with formal sign-off. Delegate sub-responsibilities to Principal Investigators and study staff. Role-based system access ensures only authorized personnel interact with each study.

Qualification CheckRole AssignmentDelegationAccess Control
04

Study Schedule & Timeline

Build visual Gantt-style timelines with phase markers, procedure windows, observation days, and sacrifice dates. Receive automated alerts when tasks are overdue. Sync with lab calendars and instrument bookings.

Gantt TimelineMilestonesAutomated AlertsCalendar Sync
05

Dosing Schedule

Configure acclimization, pre-dose baseline, treatment phases, and recovery periods with dose levels, routes (PO, IV, SC, IP), volumes, and frequencies. Auto-calculate dose volumes per body weight.

Phase SetupRoute & FrequencyDose LevelsAcclimization
06

Study Progress Tracking

Real-time dashboards show phase completion, observation status, and data entry progress per domain. Log and track protocol deviations with root cause, impact assessment, and CAPA linkage.

Live DashboardDeviationsData StatusCompletion Metrics
01
02
03
04
05
06

Structured Phase Design & Domain Collection

Model complex multi-phase studies exactly as practiced — acclimization through recovery — with domain-specific data capture mapped to each phase, group, and timepoint.

Acclimizaton
Day 1 – 7
  • Daily clinical observations
  • Body weight measurement
  • Food & water consumption
  • Environmental adaptation
  • Pre-study health screening
Pre-Dose Baseline
Day 8 – 10
  • Baseline blood sampling
  • Urinalysis
  • Ophthalmology exam
  • ECG (safety pharmacology)
  • Randomization & grouping
Treatment Phase 1
Day 11 – 28
  • Daily dose administration
  • Route: Oral gavage
  • Frequency: Once daily
  • Interim blood draws (Day 14, 21)
  • Weekly body weight & food consumption
Treatment Phase 2
Day 29 – 56
  • Escalated dose level
  • Route: IV bolus
  • TK sampling (Day 29)
  • Ophthalmology (Day 42)
  • Urinalysis collection (Day 50–52)
Recovery
Day 57 – 70
  • No dosing — reversibility check
  • Clinical observations continue
  • Terminal hematology & chemistry
  • Terminal body weight
  • Necropsy & organ weights

Study Data Domains

Clinical Signs

Daily observations, mortality, morbidity

Body Weight

Individual & group mean trends

Food Consumption

Recorded per cage per interval

Hematology

CBC, differential, reticulocytes

Clinical Chemistry

Liver, kidney, metabolic panel

Urinalysis

Volume, pH, microscopy

Histopathology

Target organ slides, H&E staining

Ophthalmology

Fundus, slit lamp examination

Safety Pharmacology

ECG, respiratory, CNS parameters

Toxicokinetics

AUC, Cmax, T1/2, plasma sampling

Neurobehavioral

FOB battery, motor activity

Organ Weights

Absolute & relative to body weight

Track Every Study, Every Day

Live dashboards surface study execution health, deviation status, and procedure completion — so nothing falls through the cracks.

12

Active Studies

47

Studies Completed

3

Open Deviations

1

Overdue Procedures

Active Studies

GLP-2024-087On Track
28-Day Repeat Dose — Rat
Treatment Phase 2 Day 42 / 70
60%
GLP-2024-091In Review
Genotoxicity — Ames & MN Test
Pre-dose Baseline Day 8 / 56 1 deviation
14%
GLP-2024-095Initiated
90-Day Sub-chronic — Dog
Acclimizaton Day 5 / 97
5%

Protocol Deviations

DEV-041 · GLP-2024-091Open

Dose administered 2h late on Day 6 due to equipment calibration

Minor
DEV-039 · GLP-2024-087Closed

Blood volume collected exceeded protocol limit for one animal

Moderate

98.4%

Procedure Compliance Rate

Built for Regulatory Confidence

Every workflow in Previa is designed with GLP compliance and regulatory submission readiness as a foundation, not an afterthought.

21 CFR Part 11
EU Annex 11
GxP Guidelines
GMP Support
GLP Standard
GCP Protocol
ALCOA+ Principles
ICH Q10 Framework

Zentixs Previa integrates with

Zentixs LIMS
Zentixs LIMS
Zentixs Spera
Zentixs Spera
Zentixs Docs
Zentixs Docs
cart
Zentixs Caliber
Zentixs Caliber
Zentixs ELN
Zentixs ELN
Zentixs Vizenta
Zentixs Vizenta

Built for Every Preclinical Discipline

Previa supports the full spectrum of preclinical safety testing across industries and study designs.

Pharmaceutical

IND-enabling studies, repeat dose tox, genotoxicity, safety pharm for small molecule drug candidates.

Biotechnology

Biologics safety — ICH S6 compliant studies for mAbs, proteins, cell and gene therapies.

Agrochemicals

Pesticide and herbicide toxicity studies per OECD and EPA OCSPP guidelines.

Medical Devices

ISO 10993 biocompatibility studies — cytotoxicity, genotoxicity, implant safety.

Chemical Safety

REACH, GHS/CLP compliant hazard classification and toxicological assessments.

CRO / Testing Labs

Multi-sponsor, multi-study management with client portals and real-time access.

Supported Study Types

Acute Single Dose Toxicity
7-Day Dose Range Finder
28-Day Repeat Dose
90-Day Sub-chronic
6/12-Month Chronic
Genotoxicity — Ames Test
Micronucleus Test
In Vitro Chromosome Aberration
Reproductive & Developmental
Carcinogenicity (104-week)
Immunotoxicity
Safety Pharmacology

Frequently Asked Questions

Preclinical study management software helps research teams plan, schedule, execute, and document animal studies through a centralized digital platform.
It creates structured timelines for study phases, procedures, dosing, observations, sampling, and milestones with automated alerts.
Previa supports acute, repeat-dose, chronic toxicity, genotoxicity, safety pharmacology, and carcinogenicity studies.
It provides role-based access, audit trails, electronic signatures, version control, and traceable study records aligned with GLP requirements.
Yes, teams can record dose levels, routes, frequencies, clinical observations, body weight, laboratory data, and other study domains.
Centralized data, automated calculations, workflow alerts, and real-time progress tracking reduce manual effort and improve study oversight.